THE INFLUENCE OF BLUE LIGHT FROM NATURAL AND ARTIFICIAL SOURCES ON THE SKIN

  • Mila Filipovic Academy of Applied Studies Belgrade, College of Health Sciences, Belgrade, Republic of Serbia https://orcid.org/0000-0002-5257-5151
  • Danijela Pecarski Academy of Applied Studies Belgrade, College of Health Sciences, Belgrade, Republic of Serbia
  • Dubravka Marinovic Academy of Applied Studies Belgrade, College of Health Sciences, Belgrade, Republic of Serbia
  • Branka Rodic Academy of Applied Studies Belgrade, College of Health Sciences, Belgrade, Republic of Serbia
  • Milica Lukic Department of Pharmaceutical Technology and Cosmetology, University of Belgrade, Faculty of Pharmacy, Belgrade, Republic of Serbia https://orcid.org/0000-0002-7934-8039
DOI: https://doi.org/10.5937/zdravzast52-44523
Keywords: blue light, skin, prevention

Abstract


Blue light includes rays of lower energy in comparison to UV radiation, but it has a greater power of penetrating the dermis, even to a depth of 1mm. The aim of this review article was to analyze the biological effects of natural and artificial blue light on the skin based on the available literature, as well as to propose preventive measures in order to protect the skin from its harmful effects. The latest research has shown that blue light has various direct and indirect effects on the skin. The direct effects of blue light on the skin are the excessive creation of reactive oxygen species, nitrogen, and hyperpigmentation, and it indirectly affects the skin by disrupting the circadian rhythm and secreting melatonin. Blue light has a direct effect on chromophores that are present in the skin and leads to their activation. Their activation leads to the excessive production of reactive oxygen species and release of reactive nitrogen species, that is, nitrogen monoxide (NO), which triggers melanogenesis and hyperpigmentation. Also, there comes to a decrease in cell vitality and/or proliferation of keratinocytes and melanocytes, then increased synthesis of pro-inflammatory interleukins and tumor necrosis factor-alpha and altered collagen metabolism. Blue light reduces the antioxidative protection of the skin by causing the degradation of present carotenoids. It can be used in clinical practice in the prevention and treatment of certain dermatoses, as well as in photorejuvenation treatments in aesthetic medicine. Further research in this field is necessary.

References

1. Suitthimeathegorn O, Yang C, Ma Y, Liu W. Direct and Indirect Effects of Blue Light Exposure on Skin: A Review of Published Literature. Skin Pharmacol Physiol. 2022; 35(6):305-318. doi 10.1159/000526720.

2. Coats JG, Maktabi B, Abou-Dahech MS, Baki G. Blue Light Protection, Part I—Effects of blue light on the skin. J Cosmet Dermatol. 2021;20(3):714-717. doi: 10.1111/ jocd.13837.

3. de Gálvez EN, Aguilera J, Solis A, de Gálvez MV, de Andrés JR, Herrera-Ceballos E, et al. The potential role of UV and blue light from the sun, artificial lighting, and electronic devices in melanogenesis and oxidative stress. J Photochem Photobiol B. 2022;228:112405. doi 10.1016/j.jphotobiol.2022.112405.

4. Austin E, Geisler AN, Nguyen J, Kohli I, Hamzavi I, Lim HW, et al. Visible light. Part I: Properties and cutaneous effects of visible light. J Am Acad Dermatol. 2021;84(5):1219- 1231. doi: 10.1016/j.jaad.2021.02.048.

5. Filipovic M, Pecarski D, Djordjevic J, Ivanovic M, Ilic V, Lukic M. Food preparation methods contribution to skin aging: a systematic review. Acta Pol Pharm. 2022;79(6): 751-761. doi: 10.32383/appdr/159417

6. Kumari J, Das K, Babaei M, Rokni GR, Goldust M. The impact of blue light and digital screens on the skin. JCosmet Dermatol. 2023;22(4):1185-1190. doi: 10.1111/ jocd.15576.

7. Regazzetti C, Sormani L, Debayle D, Bernerd F, Tulic MK, De Donatis GM, Chignon-Sicard B, Rocchi S, Passeron T. Melanocytes Sense Blue Light and Regulate Pigmentation through Opsin-3. J Invest Dermatol. 2018;138(1):171- 178. doi 10.1016/j.jid.2017.07.833.

8. Narla S, Kohli I, Hamzavi IH, Lim HW. Visible light in photo dermatology. Photochem Photobiol Sci. 2020; 19(1): 99-104. doi 10.1039/C9PP00425D

9. Duteil L, Cardot-Leccia N, Queille-Roussel C, Maubert Y, Harmelin Y, Boukari F, et al. Differences in visible light[1]induced pigmentation according to wavelengths: a clinical and histological study in comparison with UVB exposure. Pigment Cell Melanoma Res. 2014;27(5):822- 6. doi: 10.1111/pcmr.12273.

10. Garza ZCF, Born M, Hilbers PAJ, van Riel NAW, Liebmann J. Visible Blue Light Therapy: Molecular Mechanisms and Therapeutic Opportunities. Curr Med Chem. 2018;25(40):5564-5577. doi: 10.2174/09298673246661 70727112206.

11. Vandersee S, Beyer M, Lademann J, Darvin ME. Blue-violet light irradiation dose dependently decreases carotenoids in human skin, which indicates the generation of free radicals. Oxid Med Cell Longev. 2015;2015:579675. doi 10.1155/2015/579675.

12. Nakashima Y, Ohta S, Wolf AM. Blue light-induced oxidative stress in live skin. Free Radic Biol Med. 2017;108:300- 310. doi 10.1016/j.freeradbiomed.2017.03.010.

13. Campiche R, Curpen SJ, Lutchmanen-Kolanthan V, Gougeon S, Cherel M, Laurent G, et al. Pigmentation effects of blue light irradiation on the skin and how to protect against them. Int J Cosmet Sci. 2020;42(4):399-406. doi 10.1111/ics.12637.

14. De Tollenaere M, Chapuis E, Martinez J, Paulus C, Dupont J, Don Simoni E, et al. Gardenia jasminoides Extract, with a Melatonin-like Activity, Protects against Digital Stress and Reverses Signs of Aging. Int J Mol Sci. 2023;24(5):4948. doi: 10.3390/ijms24054948.

15. Lyons AB, Moy L, Moy R, Tung R. Circadian Rhythm and the Skin: A Review of the Literature. J Clin Aesthet Dermatol. 2019;12(9):42-45. Epub 2019 Sep 1.

16. Duteil L, Queille-Roussel C, Lacour JP, Montaudié H, Passeron T. Short-term exposure to blue light emitted by electronic devices does not worsen melasma. J Am Acad Dermatol. 2020;83(3):913-914. doi: 10.1016/j. jaad.2019.12.047.

17. Ceresnie MS, Patel J, Lim HW, Kohli I. The cutaneous effects of blue light from electronic devices: a systematic review with health hazard identification. Photochem Photobiol Sci. 2023;22(2):457-464. doi 10.1007/s43630- 022-00318-9.

18. Coats JG, Maktabi B, Abou-Dahech MS, Baki G. Blue light protection, part II-Ingredients, and performance testing methods. J Cosmet Dermatol. 2021;20(3):718-723. doi: 10.1111/jocd.13854.

19. Bacqueville D, Jacques-Jamin C, Lapalud P, Douki T, Roullet N, Sereno J, Redoulès D, Bessou-Touya S, Duplan H. Formulation of a new broad-spectrum UVB + UVA and blue light SPF50+ sunscreen containing Phenylene Bis[1]Diphenyltriazine (TriAsorB), an innovative sun filter with unique optical properties. J Eur Acad Dermatol Venereol. 2022;36 Suppl 6:29-37. doi: 10.1111/jdv.18196.

20. Cohen L, Brodsky MA, Zubair R, Kohli I, Hamzavi IH, Sadeghpour M. Cutaneous Interaction with Visible Light: What Do We Know. J Am Acad Dermatol. 2020;S0190- 9622(20)30551-X. doi: 10.1016/j.jaad.2020.03.115.

Published
2023/07/04
Issue
Vol. 52 No. 2 (2023): HEALTH CARE
Section
Review article